New data from CDC's Antibiotic Resistance (AR) Investment Map indicates there is early progress by states to combat AR. The map notes more than 170 state-reported successes, and each state reported multiple successes. These are the first comprehensive reports on state progress made following the first year of Congress' investment in CDC's Antibiotic Resistance Solutions Initiative. CDC Director Brenda Fitzgerald, MD, said: "This interactive map showcases the work happening on the front lines of every state and CDC's commitment to keep people safe from drug-resistant infections." CDC made investments in all 50 states, 6 large cities, and Puerto Rico in fiscal year 2016 to expand laboratory and epidemiology expertise and increase public health innovations to combat AR across health care settings, food, and communities. The new AR Investment Map shows, for example, that Michigan reduced "nightmare bacteria" carbapenem-resistant Enterobacteriaceae by 30% in 40 facilities and prevented more than 300 infections via its surveillance and prevention initiative. In addition, 38 states and 2 cities now use whole genome sequencing to monitor for outbreaks and identify AR for Listeria, Salmonella, Campylobacter, and Escherichia coli. In Kentucky, meanwhile, an aggressive and coordinated response to a rare and concerning resistance gene successfully contained the outbreak and halted its spread. A large portion of CDC's AR investments go to enhancing infrastructure in health departments across the country. Since 2016, the agency has provided $144 million to 56 state and local health departments and Puerto Rico to address this threat. Additionally, CDC has invested more than $76 million in more than 60 universities and health care partners to identify and implement new ways to prevent resistant infections and stem their spread.